@SandraJ:
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Does a jet that size, fall 35000 feet in a split second, or would there at least be a minute or 2 available for the pilots to at least notify the cabin and/or send a distress/mayday signal?
The odds are very great that the plane reached the ocean via a gross upset, that is, an extreme departure from controlled flight. Once the upset began, the time remaining before impact might have been as short as one minute, or as long as a few minutes.
In a gross upset, the flight crew would be completely absorbed by their attempts to restore control of the aircraft. Even if one pilot was making all of the flight control inputs, the other pilot would have been doing everything possible to assist the pilot flying. In such an acute crisis, I think it unlikely that the flight crew would spend the precious seconds available to them talking on the radio or intercom. If they had successfully regained some measure of control over the flight path, they would then have addressed communication.
When a jet plane enters a gross upset, the interval between a sense of normalcy (sensations not very unusual for an airline flight) and things being obviously very very wrong can be as short as a few seconds. From cases where airliners survived a gross upset, the onset has usually been very rapid.
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no life jackets were found inflated
If there was no intercom announcement of an emergency, passengers would not be instructed to put on life jackets. I would expect the cabin to be so instructed if the plane were in at least partially controlled flight, and the flight crew was preparing for ditching (controlled landing on water)
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cabin crew seats were not in use
If there was no intercom announcement of an emergency, cabin crew may have been busy with their normal duties until the upset developed. Once the upset began, the situation inside the cabin (high and changing G forces, possible extreme vibration) may have prevented the cabin crew from reaching their seats.
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Would it be reasonable to assume that the Pilots at the controls, were incapacitated
This is a possibility that a thorough accident investigation will consider.
In light of your question, the absence of voice radio communication for some time before the crash (I think at least half an hour) is especially interesting. The HF radio technique used to communicate between transoceanic flights and air traffic controller is famously undependable, and I don't know how unusual this lack of radio contact was.
I am aware of one case in which both pilots became gradually incapacitated at the same time (due to a cabin pressurization failure, that the crew did not recognize), but perhaps that was the only time this has happened on a scheduled jet airliner. This probably did NOT happen on AF447, because the wreckage was found close to the point from which the ACARS message about cabin pressure was issued.
One way that the flight crew could become incapacitated would be a large enough hailstone or other object breaking the windscreen.
There have been several sad cases where the flight crew was incapacitated by violent attack.
A more subtle "incapacity" that will probably be carefully studied, will be the effect on crew performance of flying in the middle of the night, and possibly on personal schedules that could aggravate fatigue.
I don't think that what we know about this accident tells a story that the crew was incapacitated, but it doesn't tell us that the crew was not! As with so many questions about AF447, the flight recorders would help greatly to provide answers.