One thing I think that is helpful in addressing this sort of case is the idea that theories at this point are not proven. In short, any theory which reasonably fits the facts if viable at this point, though some are markedly more likely than others.
At this point, my understanding is that around fifty bodies have been recovered, and are subject to autopsy. The vertical stabilizer, the left inboard wing spoiler, and a variety of other pieces have been recovered, though at this point no public data seems to be available regarding analysis of these pieces. The debris field is around 50 miles long.
The plane also sent out a number of automatic messages, most of which seem to be related to bad stagnation pressure measurements from the pitot tubes (interestingly the TCAS failure also cascades from this).
What we currently do not know is what sort of telemetry readings the FDR recorded, nor do we have the CVR (which would shed considerable light on crew decisions). Also the first officer had more A330 experience than the captain, though the captain had more total flight experience than the FO. All three pilots were certified for the A330, meaning that all would have been ranked "captain" on domestic flights.
Now, the initial question comes down to the group of ACARS messages from 0210Z. Each of these messages is consistent with pitot tube malfunction. These include cascading failures to the rudder travel limiter, the degradation to alternate law, the ADR disagree, and so forth. According to maintenance engineers I have talked to, the Airbus manual states that the TCAS inop fault is triggered by the ADR disagree fault. At this point air speed warnings are displayed to the AFD. So at this point we can say with reasonable certainty that the pitot tubes were blocked.
I can see three possible causes for the pitot tube failures:
1) Ice crystal ingestion. Ice crystals can block pitot tubes even where there is no "icing" activity elsewhere. This seems to be the most likely cause. (Moderate to high likelihood). For a parallel, see
http://www.atmos.washington.edu/kwajex/ops-web/aircraft/19990902/discussion.html2) Lightning damage. This would be unlikely for a couple of reasons. Airplanes are typically engineered to tolerate lightening strikes. Most lightning damage tends to be localized and minor (2mm hole in the hull, for example) around the entrance and exit points. Similarly lightning causing damage to electronic systems would tend to follow a localized damage model. To be a problem, the lightening would have to enter or exit next to the radome, and take out either the AIRU's A second reason that lightening is unlikely is that this type of storm is characterized by an unusual lack of lightening. We can't rule it out, but it seems quite unlikely. Likelihood: low to very low.
3) A small meteor strike cannot be ruled out. However there the likelihood there is very very low.
As more data becomes available, we may be able to rule out the second two possibilities and assume ice ingestion is the certain cause of the problem. At the moment, however, the other two possibilities are to be set aside as unlikely but not discarded.
A few unknowns here:
1) What were the autothrottle outputs prior to disconnect? How fast was the plane going airspeed-wise?
2) What were the pilot decisions prior to 0210Z?
3) What was the autothrust output from 0200Z through 0210Z? What was the speed of the aircraft during that time?
A lack of airspeed data by itself is insufficient to down the airplane, but combined with other factors, it could be a major contributor.
The next minute is where things go from bad to disasterous. The IR disagree error, according to some of my sources, only occurs AFTER the first inertial reference system is voted out. Hence we have IR 2 voted out prior to the error, and then IR's 1 and 3 disagreeing, while we have cascading failures to ISIS units. This means a loss of reliable attitude data. The loss of both airspeed and attitude data in a cloud at night may be an unrecoverable situation. and in fact the loss of attitude data is probably more of a serious problem than the loss of airspeed data (with airspeed out you can set thrust to known reasonable levels and have a fighting chance, with attitude data out you might not even know which way is up). As far as I can tell from schematics, the IR1 is the pilot's IR, IR2 feeds to the copilot, and IR 3 feeds to the standby. This error cascades to the flight vector warning on the Pilot Flight Display noted in another ACARS message.
IR systems are entirely closed systems and do not depend on airspeed input (they are basically gyroscopes and lasers). They supply heading, pitch, and yaw information to the pilots and computer systems.
If IR2 was not functioning at 0210Z, why? Was this a maintenance problem?
What caused the IR disagree message? An impact with something? Extreme turbulance?
I don't think the inertial reference systems are supposed to fail in this way, which suggests a systems failure on the airplane. I think the IR failure is more serious than the air data failures. Similarly, see
http://www.scribd.com/doc/2486889/Aircraft-Accident-Report-AdamAir-PKKKW. I have questions as to how well the pilots could have maintained flight in both this case and the Adam Air case in the absence of known good inertial reference data.
After this we have primary and secondary computer systems faults, followed by a compression system controller error suggesting that the differential pressure was changing rapidly. This could be a rapid decompression or simply a rapid descent.
There are a number of questions open as to whether the plane disintegrated when it hit the water or whether it broke up in the air. Here again, there are multiple theories.
The plane may have come apart in the air with the vertical stabilizer the first to separate. This would explain the large debris field. Or:
The plane may have made a less-than-high-speed landing on the water, but broke apart on impact. The people may have been killed on impact. The large debris field may be explainable by differences in current speed and direction between surface and deeper currents. This should be answerable by careful analysis of the vertical stabilizer autopsies, etc. During the Comet disasters, it was established that clothing could be removed by ocean waves, but that certain specific types of causes of death were associated with explosive decompression. Here at least, we should have answers in the near future.
It is quite possible that in the absence of airspeed and inertial reference data, the plane simply was the victim of a jet upset. The questions of "why" and "what can be done differently" will take more time to discover.